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A meta-analysis of efficacy and safety of doripenem for treating bacterial infections BJID
Qu,Xiao-Yu; Hu,Ting-Ting; Zhou,Wei.
Objective: The aim of this article is to compare the efficacy and safety of doripenem for bacterial infections. Methods: We included six randomized clinical trials identified from PubMed and Embase up to July 31, 2014. The included trials compared efficacy and safety of doripenem for complicated intra-abdominal infections, complicated urinary tract infection, nosocomial pneumonia, and acute biliary tract infection. The meta-analysis was carried on by the statistical software of Review Manager, version 5.2. Results: Compared with empirical antimicrobial agents on overall treatment efficacy, doripenem was associated with similar clinical and microbiological treatment success rates (for the clinical evaluable population, odds ratio [OR] = 1.26, 95% confidence...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Doripenem Meta-analysis Efficacy; Safety; Infection.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702015000200156
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Enhancement of chitosanase production by cell immobilization of Gongronella sp. JG BJM
Zhang,Pingping; Zhou,Wei; Wang,Peng; Wang,Li; Tang,Mingli.
Chitosanase production of Gongronella sp. JG cells immobilized in calcium alginate gel and polyurethane foam was compared with that of the free cells, there was a 60% increase in the enzyme yield (2429 U/L) compared to the highest yield obtained from free cells (1513 U/L). The optimal immobilization parameters (concentrations of sodium alginate, calcium chloride, bead inoculums, bead diameter, etc) for the enhanced production of chitosanase were determined as: sodium alginate 2% (w/v), 0.1 M calcium chloride, inoculum 10 mL beads to 100 mL production media and 2.7 mm bead diameter. Maximum chitosanase production was achieved with initial pH of 5.5 and temperature of 30 ºC. The alginate beads had well stability, retained 85% ability of enzyme production...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Chitosanase production; Gongronella sp. JG; Cell immobilization; Sodium alginate.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822013000100029
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Late nitrogen application enhances spikelet number in indica hybrid rice (Oryza sativa L.) Scientia Agricola
Zhou,Wei; Lv,Tengfei; Chen,Yong; Hu,Jianfeng; Zhang,Qiang; Ren,Wanjun.
ABSTRACT To increase rice yield potential, field experiments were conducted in farmers’ paddies in 2011 and 2012 to evaluate the effects of different nitrogen applications on the yield and panicle components of three typical indica hybrid rice varieties in Sichuan Province. The number of grains per panicle resulting from late nitrogen application (LA) was 12 % greater than that obtained from traditional nitrogen application (TA); this increase was the main source of improvements in yield. The number of surviving and differentiated spikelets (NSS and NDiS) resulting from LA was significantly higher than that measured under TA, especially for the Fyou498 cultivar, where the NSS and NDiS increased by 15 % and 14 %, respectively. Compared with TA, the number...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Panicle; Grain number; Branch; Degenerated rate; Yield.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-90162017000200127
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miR-22 and cerebral microbleeds in brainstem and deep area are associated with depression one month after ischemic stroke BJMBR
Hu,Jia; Zhou,Wei; Zhou,Zhiming; Yang,Qian; Xu,Junfeng; Dong,Wanli.
In this study, we aimed to explore the relationship among miR-22, deep cerebral microbleeds (CMBs), and post-stroke depression (PSD) 1 month after ischemic stroke. We consecutively recruited 257 patients with first-ever and recurrent acute cerebral infarction and performed PSD diagnosis in accordance with the Diagnostic and Statistical Manual IV criteria for depression. Clinical information, assessments of stroke severity, and imaging data were recorded on admission. We further detected plasma miR-22 using quantitative PCR and analyzed the relationship among miR-22, clinical data, and PSD using SPSS 23.0 software. Logistic regression showed that deep (OR=1.845, 95%CI: 1.006-3.386, P=0.047) and brain stem CMBs (OR=2.652, 95%CI: 1.110–6.921, P=0.040), as...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Depression; MicroRNA; Stroke; Cerebral microbleeds; Magnetic resonance imaging.
Ano: 2020 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2020000500611
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Phenol degradation and genotypic analysis of dioxygenase genes in bacteria isolated from sediments BJM
Tian,Mengyang; Du,Dongyun; Zhou,Wei; Zeng,Xiaobo; Cheng,Guojun.
Abstract The aerobic degradation of aromatic compounds by bacteria is performed by dioxygenases. To show some characteristic patterns of the dioxygenase genotype and its degradation specificities, twenty-nine gram-negative bacterial cultures were obtained from sediment contaminated with phenolic compounds in Wuhan, China. The isolates were phylogenetically diverse and belonged to 10 genera. All 29 gram-negative bacteria were able to utilize phenol, m-dihydroxybenzene and 2-hydroxybenzoic acid as the sole carbon sources, and members of the three primary genera Pseudomonas, Acinetobacter and Alcaligenes were able to grow in the presence of multiple monoaromatic compounds. PCR and DNA sequence analysis were used to detect dioxygenase genes coding for catechol...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Isolation and identification; Gram-negative bacteria; Substrate utilization; Dioxygenase genes; Phenol biodegradation.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822017000200305
Registros recuperados: 5
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